Nicotinamide adenine dinucleotide (NAD) is a molecule that’s found in all living cells. It plays an important role in metabolism, acting as a coenzyme in processes such as DNA repair and energy production. NAD+ is particularly important in regulating how our cells age. As we get older, our NAD+ levels decline, which has been linked to age-related diseases such as Alzheimer’s disease, heart disease, and cancer.
Recent studies have shown that supplementing with NAD+ can raise levels of this important molecule, providing a variety of potential health benefits. Here are some of the most promising Nad+ benefits that have been supported by science.
May Help Treat Addiction
NAD+ has been shown to be effective in treating addiction. In a study on rats, NAD+ was able to reduce withdrawals and cravings associated with alcohol dependence. Researchers believe NAD+ may work by helping to repair the damage caused by addiction on a cellular level.
In another study, people with alcohol dependence who were given an intravenous infusion of NAD+ reported reduced withdrawal symptoms and fewer cravings for alcohol. These findings suggest that NAD+ could be a promising treatment for addiction in humans.
May Boost Brain Function
NAD+ levels have been shown to decline with age, which may contribute to age-related cognitive decline. However, studies on animals suggest that boosting NAD+ levels could help improve brain function and protect against age-related cognitive decline. In one study, mice that were given an infusion of NAD+ showed improved mental function and had less cellular damage in their brains than mice that didn’t receive the infusion. These findings suggest that boosting NAD+ levels could help protect against age-related brain deterioration in humans as well. More research is needed to confirm these results.
Could Have Anti-Aging Effects
NAD+ plays an important role in regulating cell health and preventing damage at a molecular level. This suggests that boosting NAD+ levels could have anti-aging effects by protecting cells from damage and promoting healthy cell function. Some animal studies support this idea. For example, one study showed that raising NAD+ levels protected against muscle wasting in aging mice. Additionally, another study found that increasing NAD+ availability protected against age-related hearing loss in mice. Though more research is needed, these findings suggest that boosting NAD+ levels could help slow down the aging process in humans as well.
May Help Treat Alzheimer’s Disease
Alzheimer’s disease is characterized by the buildup of harmful proteins in the brain called plaques and tangles . This buildup leads to inflammation and cell death, eventually leading to cognitive decline . Studies suggest that boosting NAD+ levels could help treat Alzheimer’s disease by reducing the buildup of harmful proteins and preventing cell death . In one test -tube study , it was shown that supplying cells with nicotinamide mononucleotide (NMN), a molecule that helps increase NAD + levels , prevented the formation of plaques and tangles . Another test -tube study found similar results , showing that NMN was able to prevent cell death by reducing inflammation . These findings suggest that boosting NAD + levels could help protect against Alzheimer’s disease . However , human -based research is needed before any definitive conclusions can be made .
Overall, nicotinamide adenine dinucleotide (NAD) is a molecule present in all living cells which plays an array of critical roles within the body – from powering metabolism to maintaining healthy DNA . Studies show promise for the use of supplementation as means of combatting some adverse side effects of aging , including cognitive decline , addiction , muscle wasting , hearing loss , and even potentially Alzheimer’s disease . However , due solely to lack human evidence , further scientific studies are warranted before drawing any conclusions about therapeutic efficacy or long term safety surrounding Nad + supplementation in humans . That being said , if you are considering trying Nad + supplementation , remember to do so only under medical supervision given insufficient evidence currently available regarding potential side effects or drug interactions related to use .